The Deeper Genome: Why there is more to the human genome than meets the eye

The Deeper Genome Why there is more to the human genome than meets the eye Over a decade ago as the Human Genome Project completed its mapping of the entire human genome hopes ran high that we would rapidly be able to use our knowledge of human genes to tackle many inherit

  • Title: The Deeper Genome: Why there is more to the human genome than meets the eye
  • Author: John Parrington
  • ISBN: null
  • Page: 397
  • Format: Kindle Edition
  • Over a decade ago, as the Human Genome Project completed its mapping of the entire human genome, hopes ran high that we would rapidly be able to use our knowledge of human genes to tackle many inherited diseases, and understand what makes us unique among animals But things didn t turn out that way For a start, we turned out to have far fewer genes than originally thoughtOver a decade ago, as the Human Genome Project completed its mapping of the entire human genome, hopes ran high that we would rapidly be able to use our knowledge of human genes to tackle many inherited diseases, and understand what makes us unique among animals But things didn t turn out that way For a start, we turned out to have far fewer genes than originally thought just over 20,000, the same sort of number as a fruit fly or worm What s , theproportion of DNA consisting of genes coding for proteins was a mere 2% So, was the rest of the genome accumulated junk Things have changed since those early heady days of the Human Genome Project But the emerging picture is if anything far exciting In this book, John Parrington explains the key features that are coming to light some, such as the results of the international ENCODE programme, still much debated and controversial in their scope He gives an outline of the deeper genome, involving layers of regulatory elements controlling and coordinating the switching on and off of genes the impact ofits 3D geometry the discovery of a variety of new RNAs playing critical roles the epigenetic changes influenced by the environment and life experiences that can make identical twins different and be passed on to the next generation and the clues coming out of comparisons with the genomes ofNeanderthals as well as that of chimps about the development of our species We are learning about ourselves, and about the genetic aspects of many diseases But in its complexity, flexibility, and ability to respond to environmental cues, the human genome is proving to be far subtle than we ever imagined.

    • ✓ The Deeper Genome: Why there is more to the human genome than meets the eye || ☆ PDF Download by ↠ John Parrington
      397 John Parrington
    • thumbnail Title: ✓ The Deeper Genome: Why there is more to the human genome than meets the eye || ☆ PDF Download by ↠ John Parrington
      Posted by:John Parrington
      Published :2019-02-06T01:27:03+00:00

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